Glycorex Catalogue NITROPHENYL GLYCOSIDES

p-Nitrophenyl ions, -OPhNO2-p (PNP below), but not glycosides thereof, give a strong absorption at 405 nm. PNP-glycosides are useful for qualitative and quantitative studies of and with glycosidases, e.g. fucosidases, galactosidases and N-acetyl-glucosaminidases.

PNP-glycosides have also been used extensively for preparative synthesis of oligosaccharides with glycosidases (K. G. I. Nilsson, Trends in Biotechnol., 6, 256 (1988).

PNP-glycosides are also useful for covalent binding to proteins or solid phases after reduction of the nitro-group with e.g. Pd/C in ethanol to an amino-group.

PNP-glycosides may also be used for temporary anomeric protection after reduction to the amino-phenyl glycoside, acetylation of the amino group and subsequent treatment with CAN (patent pending).

if you are interested in Bulk Quantities or in Custom Synthesis of PNP-Glycosides or of PNP-Oligosaccharides, please contact us.

Cat. No.	STRUCTURE	Quantity
P-6001	GlcNAcß-PNP Substrate for ß-D-glucosaminidases	(50 mg) (250 mg) (1 g) (5 g)
P-6002	GalNAcá-PNP Substrate for á-D-galactosaminidases	(5 mg) (25 mg) (100 mg)
P-6003	Fucá-PNP Substrate for á-L-fucosidases	(25 mg) (100 mg) (250 mg) 1900 (1 g)
P-6004	Galá-PNP Substrate for á-D-galactosidases	(500 mg) (1 g) (5 g)
P-6005	Galß-PNP Substrate for ß-D-galactosidases	(500 mg) (1 g) (5 g)
P-6008	Galß1-3GalNAcá-PNP	(5 mg)

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